We observed lower effectiveness of LAIV compared with IIV against influenza A/H1N1pdm09 but not A(H3N2) or B among children and adolescents, suggesting poor performance related to the LAIV A/H1N1pdm09 viral construct. Seasonal Effectiveness of Live Attenuated and Inactivated Influenza Vaccine. . Pediatrics.
Vaksin Influenza yang Dilemahkan (LAIV) LAIV adalah pilihan vaksin influenza lainnya; berlaku bagi orang berusia antara 2 tahun hingga 49 tahun. Akan tetapi, LAIV tidak boleh diberikan kepada seseorang yang mengalami kondisi apapun berikut ini: (a) Terapi bersamaan yang mengandung aspirin atau salisilat bagi anak-anak atau remaja;
Our data provides evidence that the effect of LAIV on S pneumoniae density in children residing in an area of high pneumococcal carriage is modest and supports the wider rollout of LAIV in LMICs to help reduce the burden of influenza-related morbidity and mortality.
This is the first study to evaluate the safety and viral shedding of LAIV in Chinese healthy juveniles and adults. LAIV has many advantages. LAIV imitates natural infection, stimulating mucosal and humoral immunity without causing severe illness. LAIV was produced by growing attenuated influenza viruses in chick embryo cells . These attenuated ...
LAIV induces local inflammation in the nose , with upregulation of B‐ and T‐cell genes and Tfh cells in the draining tonsillar tissue 6-7 days after vaccination [43, 44]. LAIV induces better T fh cell responses in the tonsils and systemic antibody responses in children with lower local salivary IgA levels . LAIV induces ...
based vaccines (LAIV-CA4-RBD and LAIV-HK68-RBD) against SARS-CoV-2. Findings Substantially higher systemic and mucosal immune responses, including bronchoalveolar lavage IgA/IgG and lung polyfunctional memory CD8 T cells, were induced by the heterologous PD1-RBD-DNA/LAIV-HK68-RBD as compared with other regimens.
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